The holidays are here, and some parents of children with ADHD will come to ask their doctors: “If the child is not in class during the holidays, can the medication be stopped until school starts? In the past, the clinical treatment of ADHD in China, because of the focus on children’s learning problems, but also concerned about the side effects of drugs, often use intermittent treatment, Monday to Friday to take medication, the weekend or summer holidays such as holidays to stop medication, set “drug holiday”, in fact, this method of medication is not scientific, for children with ADHD standardized treatment is very unfavorable. In fact, this method of medication is not scientific and is very detrimental to the standardized treatment of ADHD. The current domestic and international ADHD treatment guidelines point out that ADHD is a chronic disease that requires long-term continuous treatment, and it is not recommended to set up “medication holidays”. ADHD is medically known as attention deficit hyperactivity disorder and is a long-term chronic disorder that affects children’s learning, emotions, daily life, social interactions and other aspects. During the holidays, the child’s school workload is lighter than usual, and the symptoms of attention deficit and hyperactivity are less pronounced than usual. However, the disease itself is not discontinued, and the harmful effects of the disease on behavior, emotions, parent-child relationships, partnerships, and character development do not stop because of the holidays. On the contrary because of the holidays lazy and irregular life can make the child more prone to some co-occurring problems such as Internet addiction, oppositional defiant disorder, or even encounter accidental injuries. Medications have shown positive results in improving the core symptoms of ADHD children such as attention deficit, hyperactivity, and impulsivity. Many children show some good and positive behavioral changes after a semester of treatment, and some bad behaviors from the past are corrected, but if treatment is not regular and medication is stopped when they encounter holidays, many symptoms will reappear and the condition will recur, especially in some cases where the treatment time is relatively short. This is definitely not good for ADHD treatment, as the child’s symptoms often fluctuate, which is not conducive to the formation of a good, fixed behavior pattern, and may affect the effectiveness of future treatment, affect the improvement of the child’s social functioning, and can cause parents and children to lose confidence in treatment. Some parents are particularly concerned about the side effects of medications, but in fact most common side effects can be gradually tolerated by the majority of children under reasonable treatment. Authoritative evidence from home and abroad indicates that ADHD is a long-term chronic disease that requires continuous medication and that medication can only be discontinued under the guidance of a physician after achieving complete remission and then continuing treatment for at least one year. Only long-term standardized medication and adherence to regular follow-up can improve the functioning of the affected child and prevent and reduce the emergence of co-morbidities.