Any ulcer or gangrene has a potential for infection, and infected wounds do not heal easily, so the first step is to prevent and control infection. (1) Local wound treatment: The main thing is to ensure adequate drainage of the ulcer wound and cleanliness of the wound. Stasis ulcer trauma daily available 3% boric acid or 0.02% furacilin solution wet dressing, after the reduction of secretions to saline gauze change, until the trauma buds fresh. Wet dressing method is the use of fine hole gauze with the required drug solution wet, slightly squeezed to not drip drug solution as degree, the surface dressing should exceed the edge of the wound 3 to 5 cm to prevent bacterial contamination of the wound, according to the trauma should be changed regularly. Dry gangrene should only be disinfected with iodine and alcohol, and later protected with sterile dry dressings to prevent secondary infection. All kinds of treatment should pay attention to strict aseptic operation, do not think that the wound is infected anyway and ignore aseptic operation, resulting in repeated aggravation of infection. (2) Reasonable application of antibiotics: for the wound infection is heavy, the systemic resistance is poor, can follow the medical advice to give broad-spectrum antibiotics to control the infection. (3) Pay attention to the external environment: ensure the cleanliness of the ward environment, bed sheets and patient’s skin. The skin around the ulcer wound can be gently washed with warm water and neutral soap, and then wiped dry with cotton balls. Squeezing the wound and damaging the skin around the affected area should be avoided.