Globulin is a mixture of various proteins in the serum, which has the function of improving human immunity, participating in the body’s defense, and can reflect liver lesions to a certain extent, as follows. 1. Improve human immunity: Globulin is a mixture of proteins produced by immune cells, which has a good immune function. When the body is invaded by pathogens, such as viruses and bacteria, globulin can form antigen-antibody complexes with bacteria and viruses (antigens) to protect the body from external antigenic damage. 2. Reflecting liver lesions: Globulin can be divided into four kinds: α1, α2, β and r. The increase of α1 globulin mostly suggests hepatitis infection, and the condition is mild; the increase of β globulin mostly suggests cholestatic liver lesions; the increase of γ globulin can be seen in most of the liver and gallbladder diseases, and if the γ globulin continues to be elevated without any other explanation, it often means that the condition is deteriorating; the gradual increase of α2 globulin mostly predicts the increase of the severity of the hepatitis lesions. If abnormal serum globulin levels are detected during the examination, it is recommended to consult a doctor as soon as possible for a definite diagnosis and follow the doctor’s instructions for systematic treatment.