The cause of death from heart valve disease is severe valvular insufficiency or severe valve stenosis, but the underlying cause of death is not stenosis or valvular insufficiency, but rather the onset of malignant arrhythmias, ventricular tachycardia, and ventricular fibrillation. Patients have structural changes in the heart as a result of long-term valve disease, mainly in the form of enlargement, decreased contractility of the heart, and a significant decrease in ejection fraction, even less than 40%. This group is particularly prone to sudden onset of malignant arrhythmias, ventricular tachycardia, and ventricular fibrillation. Once the attack occurs, without timely electrical cardioversion, electrical defibrillation, or chest compressions, the patient will suffer respiratory and cardiac arrest within 2-3 minutes, and eventually die from multiple circulatory failure. Therefore, mild and moderate valvular disease does not lead to patient death. Although severe valvular insufficiency or valvular regurgitation can lead to patient death, the underlying cause of death is cardiac insufficiency and sudden onset of malignant arrhythmias.