Melasma can affect both men and women, but it is more common in young and middle-aged women. The lesions are light brown to dark brown patches with different sizes and irregular shapes, smooth surface without scales, and no conscious symptoms. The pigmented patches are symmetrically distributed on the face, most obvious on the cheekbones, forehead and cheeks, sometimes in the shape of a butterfly wing, and the lesions can also involve the temporal area, nose and upper lip, but not the eyelids. In some patients, the skin pigmentation of the areola, genitalia, axillae, and groin may also deepen. The shades of pigmentation may vary with seasonal changes and the degree of sun exposure. Melasma in pregnant women may gradually fade away after delivery, but it may recur after pregnancy. The first treatment of melasma is to identify the cause of the disease and carry out prevention. The general treatment measures include: a. Topical whitening drugs, such as hydroquinone cream, arbutin, L-Vc, antioxidant complexes, sunscreen, etc. b. Fruit acid skin resurfacing, starting from 20% concentration and gradually over to 35%-50%. c. Integrated medication, common combinations include topical application of 0.025% vincristine + dinaide + 2% hydroquinone, stop using vincristine and dinaide after 2 weeks and only apply hydroquinone cream; d. Whitening injection (tranexamic acid, glutathione, Vc) e. Oral tranexamic acid + Vc + VE (with antioxidant effect); Combination of Chinese and Western medicine, using medication for internal and external use, acupuncture and other means to make melasma improve, using medical skin care products Repairing moisturizers to reconstruct sebaceous membrane, promote epidermal repair and regeneration, restore skin barrier function and enhance skin resistance to external adverse factors. The key points to prevent the recurrence of melasma are: keep your mood relaxed, avoid long-term over-stress, get enough sleep, have a balanced and reasonable diet, drink more water, eat more vegetables and fruits rich in vitamins, consume sugar, fat, protein and salt in moderation, and eat less or no food with food additives or coloring. Avoid smoking and alcohol, and use contraceptives carefully. Massage your face with both hands often on your own to promote facial blood circulation. Skin metabolism, prompting melanin loss. Sun protection, pay attention to the use of light-avoidance agents when going out or in summer, or use UV protection umbrellas to cover up. Actively treat all kinds of dermatitis on the face to prevent inflammatory hyperpigmentation. Choose high quality cosmetics and avoid using poor quality cosmetics. Although melasma cannot be cured, it can be improved, controlled and prevented.