Early pregnancy reaction is a normal physiological phenomenon. However, if vomiting gradually increases, not only in the morning and after meals, but also repeatedly and even unable to eat, the water and electrolyte balance can be imbalanced and the metabolism can be impaired, that is, it will develop into severe pregnancy vomiting, which will adversely affect the liver and aggravate the damage of the liver. As a result of prolonged vomiting and inability to eat, the synthesis and storage of liver glycogen are reduced, which can cause damage to the liver parenchyma, fatty degeneration of liver cells, and occasionally necrosis. In severe liver damage, alkaline phosphatase and transaminases in the blood are increased, blood bilirubin and urobilinogen are increased, and jaundice may appear throughout the body. It can also cause a decrease in plasma protein and fibrinogen and a tendency to bleed. Therefore, if severe pregnancy vomiting occurs, hospitalization should be promptly treated, and fluids and energy should be replenished to prevent liver damage. Pregnant women who experience severe pregnancy vomiting should pay attention to the following points: 1. Avoid excessive mental tension, relax physically and mentally, and pay attention to rest. 2, pay attention to dietary regimen: eat whenever you want, eat less and more meals to avoid the emptiness in the stomach, have some cookies, snacks, etc. ready to eat, which can relieve nausea and vomiting. Seasoning according to personal preferences to increase appetite; avoid bad smell stimulation, such as fried food, greasy smell; prevent constipation, because constipation can aggravate the degree of early pregnancy reaction, eat more vegetables, fruits; pay attention to supplement water and vitamins, you can drink fruit juice, sugar and salt water or light tea water, etc.. Through diuresis, harmful substances in the body can be excreted from the urine. 3, vomiting serious, eating difficulties should be hospitalized to prevent damage to liver and kidney function. If vomiting persists after a week of treatment, body temperature exceeds 38℃, positive urine ketone body, jaundice aggravates, delirium, lethargy, retinal hemorrhage, polyneuritis, termination of pregnancy should be considered.