Any drug has certain side effects, it is not recommended to take Cotrimoxazole Hydrochlorothiazide for a long time, it is recommended to have frequent medical checkups and dynamically adjust the drug or dosage according to the results of medical checkups. Cotrimoxazole hydrochlorothiazide is a kind of antihypertensive drug, and its main ingredients are antihypertensive ingredients such as dibazole and lisdexamfetamine, which can be used in the treatment of hypertension. However, the drug is not a first-line drug for the treatment of hypertension and is not recommended for long-term use. If side effects such as diarrhea, fatigue and drowsiness occur during the administration of Cotrimoxazole Hydrochlorothiazide, it is necessary to go to the hospital in time to adjust the antihypertensive medication. In addition pregnant and lactating women, infants and young children, patients with severe hepatic and renal insufficiency, patients with severe heart failure and those who are allergic to drug components are prohibited. Patients should choose the appropriate antihypertensive drugs according to the doctor’s recommendations in combination with their own conditions, it is not recommended to take compound dibazole hydrochlorothiazide for a long time, and it is recommended to adjust the drug or the dosage of the drug in time according to the progress of the disease.