Hyperthyroidism crisis in the early stage when the patient’s original symptoms worsen, with moderate fever, weight loss, nausea, vomiting, crisis phase is characterized by high fever or ultra-high fever disproportionate to the extent of the disease, the body temperature is often more than 40 ℃ or higher as the difference between severe hyperthyroidism and hyperthyroidism crisis is an important point of differentiation, it is recommended that the patient with hyperthyroidism crisis to timely consult a doctor. Hyperthyroidism crisis occurs in toxic diffuse goiter (Graves’ disease), occasionally in toxic multinodular goiter, for thyrotoxic patients can be life-threatening and serious manifestations, usually seen in severe hyperthyroidism in combination with other diseases such as infections, trauma, mental stress and other conditions. A large amount of thyroid hormone is released into the circulating blood, and the sudden rise of thyroid hormone in the patient’s blood is an important mechanism that causes hyperthyroidism crisis. It is recommended that patients with hyperthyroidism follow the doctor’s instructions to actively treat, the occurrence of uncomfortable symptoms, timely medical care.