Why is it common for hepatitis B patients to have comorbid hepatogenic diabetes?

  Viral hepatitis B (hepatitis B for short) is caused by hepatitis B virus, with malaise, loss of appetite, nausea, vomiting, anorexia, hepatomegaly and liver function abnormalities as the main clinical manifestations. Hepatitis B virus is a hepatophilic virus, but it can also involve other systems of the body and cause lesions in corresponding areas, such as pancreatitis, diabetes mellitus, hyperthyroidism, aplastic anemia, hepatitis B-related nephritis, arthritis, cardiomyopathy, etc.  Diabetes is a group of metabolic diseases characterized by hyperglycemia, whose main features are hyperglycemia, glycosuria, polyuria, polydipsia, polyphagia, lethargy and fatigue. Diabetes is one of the most common chronic diseases. In diabetes, the chronic damage and dysfunction of various tissues, especially the eyes, kidneys, heart, blood vessels and nerves, can be caused by the long-term presence of high blood sugar.  The liver is an important site of sugar metabolism, and chronic hepatitis or cirrhosis often causes disorders of sugar metabolism, leading to dysfunction of pancreatic islet cells in the pancreas, resulting in clinically increased urine sugar and fasting blood sugar, which is called “hepatogenic diabetes”. It is not uncommon for hepatitis B and severe hepatitis to be combined with diabetes mellitus, and studies have shown that hepatogenic diabetes mellitus in patients with chronic hepatitis B accounts for 4%.  In liver disease, the liver’s use of glucose is significantly reduced, the liver’s ability to synthesize glycogen is reduced, that is, the liver’s sugar reserve capacity is reduced, the glucose tolerance test is significantly reduced, the hepatitis B virus can be detected in the pancreatic tissue, often combined with pancreatitis, resulting in a significant reduction in insulin production, blood insulin levels are reduced, etc., are the causes of diabetes.  In patients with chronic liver disease, due to long-term damage to liver cells, the metabolism of sugar is impaired, and if treatment is not timely, diabetes occurs. found during blood tests.  Hepatitis patients need high energy to promote liver cell regeneration and repair, while diabetic patients require a low-sugar diet, so it is very important to arrange the diet of hepatitis combined with diabetes in a reasonable way.