If the symptoms of celiac disease are mild, they can be relieved by dietary adjustments. Those with severe celiac disease or complications should seek medical attention. Leg pain in children can usually be relieved by rest, massage and calcium supplementation. 1. Celiac disease is an autoimmune disease that often involves the small intestine and is mostly caused by the consumption of wheat gluten foods, manifesting itself in chronic diarrhea, abdominal pain, bloating, fatigue, weight loss, etc. In severe cases, hypoproteinemia may occur. In severe cases, symptoms such as hypoproteinemia, anemia, edema, and osteoporosis may occur. Celiac disease patients can improve their symptoms by modifying their diets with gluten-free foods such as gluten-free oats, vegetables and fruits, and supplementing with vitamin D and vitamin B12. In addition, patients should also pay attention to rest and maintain good hygiene habits to avoid complications such as perianal inflammation and perianal abscess. 2. Children’s leg pain may be caused by excessive exercise, vitamin D deficiency or calcium deficiency. (1) Excessive exercise: Excessive exercise can cause damage to joint muscles, which usually results in leg pain and other symptoms, which can be relieved by proper rest and local massage. (2) Vitamin D deficiency or calcium deficiency: it can lead to localized pain in the lower limbs, muscle spasms and other symptoms, which can be treated with appropriate vitamin D supplementation and calcium supplementation. If children have celiac disease leg pain and other symptoms, it is recommended to go to the regular hospital in time, after clarifying the cause of the disease, under the guidance of the doctor for targeted treatment.