Urine protein, such as in strenuous exercise, high protein diet and other physiological conditions, after resting or drinking a lot of water, urine protein is likely to disappear; such as in acute and chronic glomerulonephritis, nephrotic syndrome, lupus nephritis, and other pathological conditions, it is usually difficult to disappear after drinking water, and some patients can be exacerbated by drinking a lot of water. 1. Physiological conditions: urine protein, such as in the case of strenuous exercise, high protein diet, standing for a long time, etc., after resting or drinking a lot of water, urine protein is likely to disappear in the urine test. 2. Pathological conditions: urine protein, such as in acute and chronic glomerulonephritis, nephrotic syndrome, lupus nephritis, diabetic nephropathy, hypertensive nephropathy, IgA nephropathy and other diseases, generally drink water after urine test urine protein will not disappear, and if a lot of drinking water, but also lead to further aggravation of the condition. If you find urine protein, we recommend that patients seek medical attention as soon as possible, and follow the doctor’s instructions to standardize the diagnosis and treatment, so as to avoid further deterioration of the condition.