The most common treatment for severe symptoms of cholecystitis, gallbladder stones and gallbladder polyps is cholecystectomy, including both laparoscopic and open cholecystectomy. Regardless of the method, it will always leave some psychological concerns to patients, ” removal of the gallbladder, the impact on eating”, “gall is gone, how to digest food”, the clinical hepatobiliary surgeons face a lot of patients targeted to solve the problem, so, after the gallbladder removal How much does it affect the body? The impact of a treatment on the body is evaluated from two perspectives: the immediate and the long-term impact. In the case of laparoscopic cholecystectomy patients, front-line clinicians have a deeper understanding of this, because patients with post-operative discomfort will mostly go back to the surgeon for treatment. Of course, there are a few patients who report occasional pins and needles in the right upper abdomen even a few months after surgery, which is related to the adhesion and pulling of the intestinal ducts. What is the role of the gallbladder? This is what patients are most concerned about before the gallbladder is cut. They think that the gallbladder has the function of digesting food and secreting bile, so naturally, without gallbladder, the digestive function is half as short as others. In fact, to use an analogy, the gallbladder is comparable to a small pond next to a reservoir, which can be filled with water to cushion the pressure of the reservoir’s capacity. Bile is secreted by the liver, and the gallbladder only plays the role of temporary storage of bile, and in turn, the gallbladder plays the role of regulating bile secretion. What are the long term effects of gallbladder removal on the body? In fact, there is no unanimous conclusion in the academic field, because there is no rigorous statistical data to date to prove the validity of this view. Long-term follow-up of patients who underwent cholecystectomy for gallbladder disease showed a significant improvement in quality of life, and in the long run, the benefits of resection far outweighed the benefits of not having it. Excision for gallbladder stones eliminates the risk of gallbladder stones turning into bile duct stones, and excision for multiple polyps or large polyps removes the risk of gallbladder cancer.