52 years old if the menstruation has not been clean, should be highly serious. Ultrasound examination is needed to understand the condition of the endometrium, if there is endometrial thickening, endometrial echogenicity is uneven, endometrium has abnormal massification, timely diagnostic scraping is given, and the scraped tissues are sent to the pathology laboratory to exclude the possibility of endometrial organism lesions. It is also necessary to do blood routine and clotting time examination, mainly to understand whether it is due to thrombocytopenia or clotting time abnormality caused by menstrual bleeding. Most women have entered perimenopause at the age of 52, when the hormone levels in the body are basically disturbed, so some functional uterine bleeding may occur in the clinic, but we must exclude organic lesions before giving medication.