Adverse reactions usually start to appear when taking Tegio after 3~7 days. 1. Gastrointestinal reactions can occur when taking Tegio for 3~5 days, and patients may experience nausea, vomiting, loss of appetite, abdominal distension, diarrhea and other symptoms. 2. When patients take Tegio for about 10 days, bone marrow suppression may occur, and after laboratory tests, blood cells are found to be decreased, anemia, easy to be infected, and reduced immunity. 3. When taking the medicine for about one month, patients may have symptoms of liver function damage, right upper abdominal pain, jaundice, anorexia, fatigue and other adverse reactions. If these symptoms occur when taking Tegio, you should actively contact your specialist and take the medicine as prescribed by your doctor to minimize the occurrence of adverse reactions.