Diabetic patients with significantly high blood glucose in the course of glucose-lowering treatment need to pay attention to the following points: 1. Strict dietary control, control the daily total calorie intake, and the daily carbohydrate intake should be fixed. At the same time, increase the intake of protein and vegetable foods, avoid fried foods and foods with high sugar intake, and ensure that the weight is within the standard weight to avoid being too light and too heavy. 2. Exercise and exercise, diabetic patients with significantly elevated blood glucose >16.7mmol/L need to suspend exercise. Patients with blood glucose <16.7mmol/L should strengthen exercise and exercise for at least 30 minutes a day, including brisk walking, jogging, strolling, gymnastics and other aerobic exercise. 3. Adjust glucose-lowering drugs, and further evaluate the patient's pancreatic function in case of obvious blood glucose elevation. According to the patient's pancreatic function, timely adjustment of hypoglycemic drugs, if necessary, the application of insulin to control blood glucose, so that blood glucose control up to standard.