Drinking alcohol is not recommended 6 hours after taking cephalosporin. Especially for cefmetazole, cefamandole and cefoperazone taken, drinking alcohol will produce a disulfiram-like reaction, which will seriously endanger health. When disulfiram-like reactions occur in patients, facial and general skin flushing, macular rash, vascular pulsation in the neck, dizziness, headache, nausea, vomiting, rapid heartbeat, and in severe cases, patients may also experience difficulty in breathing, chest tightness, chest pain, and even impaired consciousness, convulsions, incontinence, drop in blood pressure, and death. Therefore, clinically, patients are generally asked not to drink alcohol after using cephalosporin. If a patient takes cephalosporin and drinks alcohol 6 hours after taking it, he can drink more glucose water or fruit juice to accelerate the oxidative decomposition and metabolism of alcohol in the body and promote the excretion of alcohol in the body. Also pay attention to monitoring the patient’s blood pressure and heartbeat. If the patient has symptoms such as obvious chest tightness, chest pain, difficulty in breathing and blurred vision, it is recommended to call 120 to the hospital in time.