Salvia miltiorrhiza is a kind of traditional Chinese medicine which has the functions of activating blood circulation, removing blood stasis, promoting menstruation, relieving pain, cooling blood and eliminating carbuncles, clearing the heart and removing vexation. Taken in moderation, it does not harm the liver, but is helpful in the prevention and treatment of liver insufficiency and cirrhosis. There is no clinical study that clearly indicates that Salvia miltiorrhiza has the effect of injuring the liver, but in the case of overdose, it may have adverse effects on patients with liver circulation disorders, such as cirrhosis and other liver insufficiencies, where intrahepatic hemodynamics may change due to the effects of the disease. That is, the patients themselves may have bleeding tendency, as evidenced by bleeding from the gums and nasal cavity, and women may show signs of excessive menstruation. And danshen has tanshin, tanshinone, protocatechuic aldehyde and other components, with inhibition of platelet aggregation, anticoagulation, reduce blood viscosity and other effects, overdose of the case may cause patients with liver disease bleeding time is prolonged, or even aggravate the bleeding symptoms. However, when overdose of Salvia divinorum is taken, compared to the liver injury effect that may be caused, the patient shows more obvious gastrointestinal irritation, such as nausea, vomiting, loss of appetite, diarrhea and other side effects that may occur. It is not recommended for patients with gastritis, gastroduodenal ulcer, esophagitis, etc..