Neonatal umbiliculitis is caused by infection of the umbilicus by Staphylococcus aureus, Escherichia coli or Streptococcus haemolyticus due to improper handling during or after birth. It is one of the common diseases in newborns, and serious complications such as sepsis can also occur if left untreated. Due to the general emphasis on disinfection and care of the umbilical cord, umbiliculitis has become less common in urban areas, but is still quite common in remote mountainous and rural areas. After the umbilical cord of a newborn is broken, the tissues of the broken part have to be absorbed slowly, and there will be white blood cells and macrophages on it when it is absorbed. There are also similar things that look like secretions, which are very easy to breed bacteria. In addition, the connective tissue around the umbilicus is very loose, making it easy for bacteria to infect and spread. In mild cases, the umbilicus may show signs of redness, swelling and oozing, and it is important to see a doctor promptly. In severe cases, the umbilicus may have a large amount of purulent discharge and bad odor, and the area around the umbilicus may be hard and swollen, which is very serious and requires immediate emergency medical attention. In mild cases of neonatal umbilicus, keep the area dry and change diapers regularly to prevent urine contamination. Clean the area with iodine, iodophor or 75% alcohol 2-3 times a day. In severe cases, if there is obvious pus in the umbilicus, diffusion around the umbilicus or systemic symptoms, in addition to local disinfection, appropriate antibiotics can be used according to the results of umbilical secretion smear or bacterial culture. Chronic umbiliculitis can form granuloma and surgical treatment can be considered. Umbilical fistula caused by closure of the ileocecal end of the yolk duct but not the umbilical end often results in mucus secretion from the umbilicus, which can easily lead to secondary infection and requires further consultation with a pediatric surgeon.