Case Study: The 42-year-old Ms. Xue had no idea that her appendicitis had turned into adnexitis and that her pelvic cavity was extensively adherent, with her uterus and bilateral adnexa immersed in pus, so she had to have her uterus and adnexa surgically removed to save her life. The symptoms of adnexitis and appendicitis in women are similar and can be easily misdiagnosed. If adnexitis is not detected in time and the attack is delayed, it can lead to pelvic inflammatory disease, which can easily spread and involve the entire lower abdomen if not seen in time, delaying treatment; patients may die because of the occurrence of infectious shock. Women should take care of themselves, and if they are unwell they must go to a regular hospital for examination and treatment in time. So, how can adnexitis and appendicitis be distinguished? 1. Before the onset of acute adnexitis, the patient will have abnormal vaginal discharge, such as purulent inflammatory discharge and increased leucorrhea. 2. The pain of appendicitis is somewhat different from the pain of adnexitis. The pain of appendicitis is unbearable, and the patient will experience severe throbbing pain in the right lower abdomen and constipation. The most important feature of appendicitis is the metastatic right lower abdominal pain, i.e., the pain is mostly around the umbilicus at first, but slowly becomes fixed in the right lower abdomen, and there is a significant rebound pain, some patients also have abdominal muscle tension, nausea and vomiting, fever, etc. Adnexitis, on the other hand, is not usually associated with rebound pain in the lower abdomen, but is initially limited to lower abdominal pain, mostly bilateral, and rarely associated with vomiting. Unlike the metastatic pain of appendicitis, the location of pressure pain in the lower abdomen in adnexitis is mainly evident above the midpoint of the inguinal ligament. Because of the close proximity of the appendix and adnexa, it is easy to misdiagnose the disease, and appendicitis can spread to the adnexa, or both. It is difficult to distinguish between the two simply by the symptoms, so it is recommended to seek medical attention and have ultrasound performed to identify and confirm the diagnosis. It is important to distinguish between appendicitis and adnexitis. If you can’t tell the difference between the two, it’s important to consult a professional, and you should also do your best to prevent and check the disease in general, so you don’t find out until later.