Itching on the body during sleep is mainly due to excitation of the vagus nerve at night and causes itching. It is mainly caused by pruritus, in the treatment can be oral levocetirizine hydrochloride capsules, external application of glyburide lotion 2 times / day for the application of treatment. In case of wind and skin eruptions, urticaria may be more likely, which can be treated with oral Avastin capsules, combined with levocetirizine hydrochloride capsules and topical glycolic acid lotion. If there are tiny papules between the fingers and around the umbilicus, and tunnels drilled by scabies, and large nodules on the vulva and buttocks, scabies may be considered more likely, and it can be treated with topical sulfur ointment or clomid ointment.