Craniosynostosis occurs in the midline of the skull and can occur at the top and base of the skull. It is more common in the occipital area and also in the top of the frontal area; in the base of the skull, it can bulge from the root of the nose, nasal cavity, nasopharynx or orbit. The main symptoms are: craniofacial malformation, intracranial hypertension, cerebrovascular arteriovenous malformation, cerebral occupational lesions, oblique head malformation, and periodic drowsiness and anorexia. The etiology of congenital malformations of the skull and brain is diverse and can be broadly classified into two categories: congenital and acquired, and Naef (1958) proposed a multivariable etiology for this disease. (1) Congenital brain penetration malformation It is generally believed that congenital prolapse malformation is related to developmental abnormalities during the embryonic period or maternal nutritional disorders, and may also be related to genetic factors. malformations. (2) Acquired cerebral penetrating malformation Acquired cerebral penetrating malformation is caused by various causes of brain tissue destruction, including birth injury, craniocerebral trauma (especially craniocerebral firearm injury), intracranial hematoma, intracranial inflammation, asphyxia, brain surgery, cerebral infarction, and other diseases that cause cerebrovascular circulation disorders. In addition, cerebrospinal fluid circulation disorders, ventricular puncture, hydrocephalus, spontaneous rupture of benign intracranial cysts into the ventricles and brain degenerative diseases may also be its etiology.