1.Surgical complications of testicular cancer Surgical treatment of testicular cancer will remove one testicle, but it will not cause infertility and will not affect sexual function, but if the surgery involves lymph nodes, then it is likely to cause difficulty in ejaculation after the surgery and affect sexual function. 2.Complications of radiation therapy for testicular cancer Radiation therapy can interfere with sperm production and cause infertility. For some men, sperm production may be restricted for a year or two years to eventually heal. 3. Chemotherapy for testicular cancer Certain chemotherapy drugs can cause infertility.