Tuberculosis liver injury may be caused by the use of anti-tuberculosis drugs, and may consider stopping the drugs, adding liver protection drugs, and so on. Commonly used anti-tuberculosis drugs are isoniazid, rifampicin, pyrazinamide and ethambutol. The first three drugs can cause liver function damage, when not sure which drug caused, can consider stopping all the drugs or stop using the most likely rifampicin first, continue to observe the changes in liver function, according to the changes in the adjustment of the drug, if necessary, add liver protection drugs. Rifampicin accumulates in the liver after oral administration and is mainly excreted through bile. If there is a transient increase in aminotransferases after taking the drug, the drug can be continued and observed with additional liver-protecting drugs; if jaundice occurs, the drug must be stopped. In conclusion, if the liver function damage is not serious, you can consider continuing to use anti-tuberculosis drugs, and at the same time add liver protection drugs for treatment and observation; if the liver function continues to deteriorate after review, the drug should be stopped immediately. The most important thing is to go to the hospital in time.