The heart, liver, spleen, lungs and kidneys, although the kidneys are ranked last in the five organs, but its role is the most important. If the kidney is compared to a “boiler”, then the “cinder” produced by the body after burning must be discharged through the boiler. Once the “boiler” problems, waste can not be discharged, not only will damage the “boiler”, the whole system will collapse. The kidneys have three main functions 1, is to produce urine, to maintain the water balance. “Each kidney in the human body has about 1.3 million glomeruli, which can filter and clean 200 liters of blood every day, equivalent to 10 buckets of drinking water, forming about 1.8 liters of urine. When there is too much or too little water in the body, the amount of urine is regulated by the kidneys to maintain the water balance in the body.” 2. It is the excretion of metabolites and toxic substances from the human body. “Human metabolism produces metabolic wastes, such as urea, uric acid, creatinine, etc. The kidneys maintain normal physiological activities by excreting these wastes from the urine.” 3. It is the endocrine function. Such as secretion of erythropoietin to promote bone marrow hematopoiesis; generation of active vitamin D to regulate calcium and phosphorus metabolism and maintain the normal structure and function of bones; secretion of vasoactive substances to regulate blood pressure, etc. It is because the kidneys have these three functions, so when the kidneys have problems, other parts of the body will also have problems. The early stage of kidney disease is mostly fatigue, weakness, puffy eyelids, pale face, large amount of foam in urine, painful or difficult urination. Next, it will produce loss of appetite, nausea and vomiting, back pain, increased nocturnal urination, generalized edema, elevated blood pressure, breath with urine odor, bone pain, itchy skin, muscle tremor, numbness in hands and feet, and slow reaction. If it becomes severe, the above-mentioned various symptoms continue to worsen, while leading to multiple organ failure such as heart, liver and lung function.