Pain in the reflex zones of the ascending and descending colon may be caused by diseases such as colitis, which can be treated by rubbing the abdomen to relieve the pain or by using medications to fight inflammation. Pain in the reflex zones of the ascending colon is usually on the right side of the abdomen, and pain in the descending colon is on the left side of the abdomen. The presence of pain in the reflex zones of the ascending and descending colon may be caused by chronic colitis, ulcerative colitis, etc., and is usually accompanied by symptoms such as abdominal distension and diarrhea. Inflammation stimulates the intestinal mucosa, and pain occurs when spasms occur in the ascending and descending colon area. Mild pain can usually be rubbed on the abdomen, or use a hot water bag on the stomach, temporary relief of symptoms. If necessary, you need to use anti-inflammatory drugs under the guidance of a doctor, such as Liuzosulfapyridine tablets, mesalazine, etc., to relieve inflammation and reduce pain. If there is frequent pain in the reflex zone of the ascending and descending colon, you should go to the hospital in time to do colonoscopy, stool routine and other tests to make a clear diagnosis, and if it is only intestinal spasm, you can use antispasmodic and analgesic drugs, such as pivoxyl bromide, under the guidance of a doctor for treatment.