A spindle cell lesion is a morphological description of a cell that is often considered abnormal and may even progress to malignancy. Spindle cell lesion is a diagnosis of cytomorphology, which describes the appearance of the cells, which have a certain degree of malignancy or have progressed to malignant tumors. Therefore, after surgical resection of these patients, it is important to follow up and observe whether there is local recurrence, and if necessary, further immunohistochemical examination. If the patient has a local recurrence, it may even progress to cancer, so it should be timely surgical resection, and laboratory tests again. Therefore, spindle cells belong to a kind of cells with potential malignant tumor and should be closely monitored after surgical resection.