Some elderly people walk with a hobbled gait, have painful knees when going up and down stairs, and even have “O” shaped legs, which is actually osteoarthritis at work. Osteoarthritis, commonly known as “long bone spurs” and “osteophytes”, is a group of diseases caused by a variety of causes of damage to the integrity of joint cartilage and related symptoms and signs. Although it is manifested in “spurs”, the underlying cause is the destruction of articular cartilage, softening of the cartilage matrix and loss of elasticity, loss of strength, and the formation of sclerosis or cystic changes of the subchondral bone and bone redundancy. This results in pain and movement disorders, leading to severe disability of the affected limb. In short, although osteoarthritis starts from the articular cartilage, it affects the entire joint structure, including the subchondral bone, ligaments, synovial membrane, joint capsule and extra-articular muscles, and eventually results in joint deformity and loss of function due to total loss of articular cartilage. When suffering from osteoarthritis, the joints often show the following symptoms: 1. joint pain, swelling and pain, especially when walking long distances, strenuous exercise, cold or rainy days. 2.Difficulty in going downstairs, both knees are weak when going downstairs, easy to fall; pain and stiffness when squatting up. 3.There is a ringing sound or palpable bone friction sound in the knee joint during passive movement. 4. A few patients may have transient joint swelling and effusion. 2. Physiotherapy includes local baking or hot compress, pay attention to avoid wind and cold, moderate activity. Drug therapy is divided into external, local injection and internal: (1) if the pain is limited, patients can use external bone paste or non-steroidal anti-inflammatory drugs in latex form, which can play a better pain relief effect; (2) local intra-articular injection of sodium hyaluronate, which is similar to joint lubricant, can play a role in nourishing the joint surface and reducing inter-articular wear; (3) oral non-steroidal anti-inflammatory drugs and articular cartilage nutrients, which can (3) oral non-steroidal anti-inflammatory drugs and articular cartilage nutrients, which can play the role of anti-inflammatory and pain relief and joint surface protection respectively. 2.Middle-term treatment is based on arthroscopic surgery. At this time, it is difficult to completely eradicate the pain caused by articular cartilage damage and bone growth through drugs. Arthroscopy is a minimally invasive procedure that can repair the damaged cartilage surface, remove the excess bone redundancy and/or remove the free body, which is an effective treatment method for mid-stage joint degeneration. 3. Late stage treatment is based on joint replacement. At this time, the local articular cartilage of the patient has basically disappeared, and the friction of the joint surface during weight-bearing is bone-to-bone friction, not cartilage-to-chondral friction. At this time, drug treatment can only provide temporary relief, arthroscopic surgery has no room for operation (can not solve the problem of cartilage loss), only through artificial joint replacement can relieve the patient’s pain and restore a normal life.