IgA clinically refers to IgA nephropathy, a kind of glomerulonephritis, which is called IgA nephropathy because immunoglobulin A deposits are visible in the glomerular basement membrane during pathological examination. Clinically, it can be divided into secretory type and serous type, of which serous type accounts for 95%. IgA nephropathy can manifest as hematuria and proteinuria, and hematuria can be divided into microscopic hematuria and carnitic hematuria with or without hypertension and abnormal renal function. If accompanied by mild proteinuria, it can be treated with ACEI or ARB drugs, the most commonly used clinically are valsartan and benazepril. Some IgA patients do not have any clinical manifestations and only show mild hematuria, which is recommended to be reviewed every 3-6 months without drug treatment. Meanwhile, if abnormal renal function occurs, active renal preservation therapy is recommended.