There are many cases of itchy calves that do not necessarily indicate diabetes. Although diabetes can manifest as skin lesions such as itchy skin or rashes. However, most diabetic itching manifests as itchy skin tissue throughout the body and is not limited to itchy calves. If it is itchy calves, the following causes should be considered for identification. First, the presence of mosquito bites or specific pathogenic bacteria such as fleas and cockroaches that can cause local itching and even scarring that lasts 1-2 months. Second, elderly pruritus in the elderly, can also appear itchy and ineffective with medication. In addition, there are no connective tissue diseases, such as dry syndrome, which can also trigger itchy calves. There are many cases of itchy calves, which should be evaluated in the context of the patient’s underlying disease, age, and general condition.