Melasma, also known as liver spots, is a yellowish-brown pigmentation on the face. It is mostly distributed on the cheeks in a symmetrical butterfly shape. It is mostly seen in women, and its onset is related to pregnancy, long-term oral contraceptive use, menstrual disorders, long-term outdoor activities, lack of sleep and other reasons. Clinical manifestations: The damage is yellow-brown or dark brown patches, often symmetrically distributed on the cheek and cheek area, but also involving the periorbital area, forehead, upper lip and nose, and the edges are generally more obvious. There are no subjective symptoms and general discomfort. The shades of pigmentation are related to season, sunlight and endocrine factors. Mental stress, staying up late and exertion may aggravate the lesions.