Melasma is a common female facial cosmetic skin disease, often symmetrically distributed on the upper eyebrow, upper lid, upper jaw, back of the nose, upper lip and other light-oriented skin surface, mostly in the form of butterfly-shaped, brown pigmented spots. Most of them have no clear cause, but some of them have clear causes, such as pregnancy, oral contraceptives, menstrual disorders, sun exposure, insomnia, nutritional deficiencies, psychological stress, overwork, improper skin care, liver disease, etc. Treatment is a comprehensive treatment in many aspects: 1, eliminate the causes. 2, absolute sun protection – three wear. 3, oral anti-pigmentation drugs. 4.Topical anti-pigmentation drugs. 5.Appropriate skin care. 6.Laser treatment. 7.Psychological care. The above treatment usually takes 3 months and is prone to recurrence. Laser treatment generally uses large spot low energy Q-switched 1064 laser, once a week, about 10 times more. It is more effective for melasma with better medical compliance, psychological tolerance and completion of enough treatments. It is less effective for those with deeper pigmentation, clear borders and large areas.