Fetal left ventricular strong echogenic foci may be a normal physiological phenomenon, but also may suggest the possibility of fetal congenital heart disease, chromosomal disorders and so on. 1. Physiological phenomenon: generally single, strong echogenic foci <2mm, most of the cases are relatively normal physiological conditions, and there is no organic cardiac lesions. 2. Fetal congenital heart disease: general dynamic monitoring of fetal left ventricular echogenic foci do not disappear or continue to increase, need to be combined with echocardiographic examination for the diagnosis of congenital heart disease. 3. Possibility of chromosomal diseases: if the strong echogenic foci are large and persistent, it is necessary to do an amniocentesis, non-invasive DNA or umbilical cord blood test to rule out the possibility of trisomy 21 or trisomy 18. It is recommended to do regular monitoring of fetal cardiac dynamics and Down’s syndrome screening during pregnancy, and perform amniocentesis if necessary, and do perinatal health care according to the results of the examination under the guidance of the doctor.