The following possibilities should be considered when labia majora edema occurs in clinical practice: first, labia edema caused by inflammatory diseases, mostly with abnormal secretions, localized edema and pain in patients; second, labia edema caused by allergies, such as labia edema and pain after patients use certain drugs, condoms or after intercourse or contact with foreign objects; third, trauma can lead to labia edema; fourth, in the middle and late stages of pregnancy or When women have tumor diseases, the compression of uterus or larger tumor can cause obstruction of venous return or lymphatic return, which can cause patients to have hereditary edema, and patients have no obvious clinical discomfort, but only feel a slight downward feeling, and the edema will be significantly reduced after patients lie down and rest.