No taste in the mouth and no appetite need to be treated according to the cause, the common ones are indigestion, zinc and vitamin A deficiency, gastroesophageal reflux, and you can choose medication and adjust your lifestyle. 1. Indigestion: Decreased digestive function results in decreased appetite and no taste in the mouth. You can improve the diet structure, choose easy-to-digest food, avoid stimulating food, and quit smoking and drinking. You can also choose medication according to the situation, such as domperidone to promote gastrointestinal power. 2. Zinc and vitamin A deficiency: Long-term deficiency of zinc and vitamin A can easily lead to abnormal sense of taste and loss of appetite. It can be supplemented with food, such as carrots and fish. In addition, nutrients containing zinc and vitamin A can be applied. 3. Gastroesophageal reflux (GERD): The stomach contents refluxing into the mouth will easily feel tasteless, and there may also be a decrease in appetite. You can choose acid-suppressing medication such as omeprazole, together with domperidone, a drug that regulates gastrointestinal motility. Mouth tasteless no appetite may have other reasons, it is recommended to go to the hospital in a timely manner, improve the examination to clarify the cause of the disease, to give targeted treatment or treatment. The medication should be taken under the guidance of a doctor.