Clinical application of 80w KTP laser vaporization in the treatment of large volume prostatic hyperplasia OBJECTIVE: To investigate the clinical application of 80w KTP laser in the treatment of large volume prostatic hyperplasia. METHODS: A retrospective study was used to treat 156 patients with prostate enlargement >60 ml with 80W KTP laser vaporization (PVP). Preoperatively, prostate volume, serum sodium as well as hemoglobin levels were observed. Intraoperative bleeding volume and operative time were recorded. Serum sodium and hemoglobin levels were observed on the first postoperative day. The duration of postoperative indwelling urinary catheter and postoperative hospital stay were observed. RESULTS: With epidural anesthesia, all surgeries were successful, and there was no one case of intermediate open surgery. The mean preoperative prostate volume was (88.9±27.1) ml, intraoperative bleeding volume (60.8±24.1) ml, and operative time (110.9±29.7) min. no 1 case required blood transfusion. The duration of postoperative indwelling urinary catheter was (2.1±0.7) days. There was no significant change in hemoglobin level and serum sodium between preoperative and postoperative periods. The postoperative hospital stay was (3.2±1.1) days. CONCLUSION: PVP is ideal for the treatment of large volume prostatic hyperplasia because it has the advantages of less trauma, fewer complications, and safety. [Keywords]: 80w KTP, laser vaporization, large volume, prostatic hyperplasia A retrospective study was conducted to select patients with large volume BPH treated by PVP at the Urological Minimally Invasive Center of Shandong Provincial Hospital between October 2004 and December 2005, and to explore the changes of KTP laser in the treatment of large volume BPH by analyzing the changes of intraoperative bleeding, operative time, postoperative indwelling urinary catheter time, and postoperative hospitalization time, etc. The effectiveness and safety of KTP laser in the treatment of large-volume BPH were explored by analyzing the changes of intraoperative bleeding, postoperative indwelling time, and hospital stay. DATA AND METHODS I. Clinical data 1. General data: In this study, a prostate with a volume >60 ml was defined as large volume BPH [1, 2]. The selected 156 patients were aged 65-92 years, with a mean of (72.7±6.8) years. History of dyspareunia ranged from 4 to 20 years, with a mean of (10.1+4.7) years. Prostate volume was calculated by ultrasound examination from 62 to 157 ml, with a mean of (88.9±27.1) ml. 28 patients had a history of acute urinary retention. Serum sodium 134-146 mmol/L, mean (138.0+2.9) mmol/L. Hemoglobin level 95-145 g/L, mean (123+15.6) g/L. PSA 0.2-17.5 ng/ml. preoperative PSA examination and MRI prostate scan were mandatory in all patients. According to the analysis of the results of both, 12 cases with PSA>10ng/ml and MRI suspected prostate cancer were excluded from prostate cancer by rectal puncture biopsy. 2. Preoperative preparation: oral antibiotics were given 3 days before surgery. For those with elevated creatinine due to prostatic hyperplasia, continuous urine drainage was performed until creatinine dropped to a stable level. Stop anticoagulants for 1 week before surgery for those taking oral anticoagulants. Diabetic patients should apply insulin to control fasting blood sugar