Segment S2 of the liver is the upper segment of the left outer lobe of the liver. The term “segment S2 of the liver with small cysts” means that there are cysts of the liver in the upper segment of the left outer lobe of the liver with small lesions. Hepatic cysts are common benign lesions of the liver, usually congenital cysts are the most common. Depending on the location and size of the lesion, the clinical manifestations of the patient vary. Smaller lesions are usually asymptomatic, while larger lesions may present with discomfort in the corresponding area of the liver and dull pain in the liver, etc. In case of co-infection, fever and pain may also occur. In terms of treatment, if the lesions are small, they usually do not require treatment, as long as they are followed up and the growth rate of the lesions is observed.