The life expectancy of patients with cerebral infarction is not only related to the size of the infarct, but also influenced by many factors. The patient’s past medical history, physical condition and the severity of the infarct can affect life expectancy. However, acute cerebral infarction that has been treated and stabilized is generally not life-threatening. The prognosis of patients with cerebral infarction is related to the location of the infarction, whether it affects the corresponding functional area, the size of the infarct, the patient’s vascular condition, and whether the patient has a history of hypertension, diabetes, coronary heart disease, atrial fibrillation, smoking and alcohol consumption, and other risk factors. However, patients with large cerebral infarction will generally be left with more serious disabling sequelae, such as unfavorable speech and hemiplegia, due to the large size of the lesion and the number of functional brain areas affected, and patients may not be able to take care of themselves and their quality of life will be seriously reduced compared with before. In addition, cerebral infarction itself does not necessarily lead to the patient’s death directly, but patients with large cerebral infarction may need to be bedridden for a long time due to severe hemiparesis and eventually endanger their lives due to complications such as pulmonary infection, urinary tract infection and decubitus ulcer, so comprehensive treatment and care for patients with large cerebral infarction is very important and is the key to reducing the risk of death. In conclusion, how long a patient with massive cerebral infarction can live cannot be generalized. The majority of patients with mild cases and most patients with severe cases will not be affected by effective treatment, and for patients with massive cerebral infarction, the level of care is also an important factor in prolonging the patient’s life.