Eruptive blisters are herpes that rise above the skin and contain watery fluid. Most of the blisters form as a result of inflammatory reactions such as those caused by bacteria, viruses, parasites (scabies) or allergic reactions, commonly pemphigus, herpes-like dermatitis and herpes zoster. Skin test examination of erosive blisters: Skin test is the most commonly used specific examination, including patch, scratch, prick and intradermal injection. Clinically, prick and intradermal test are most commonly used, such as negative prick test; can be reviewed for intradermal test. Methods and principles: specific patients can be induced to produce specific IgE after exposure to allergens, this antibody adheres to the IgE receptor on the surface of the mast cells in the skin or submucosal layer, when it meets with the allergens that re-enter the body to form a bridge between one allergen and two IgE antibodies, resulting in a series of biochemical processes occurring in the mast cells, releasing allergic mediators, which can cause localized skin flushes, halos, or itching. Itching. Methods: In the patient’s inner forearm, routine disinfection, and then use OT syringe, No. 4 injection needle inhalation of different allergens dipping solution were injected into the inner forearm intradermal 0.02 ml, the distance between the antigenic points is 2.5 cm. 15-20 minutes after the skin test, observation of the skin reaction, 132 local air bubble and the size of the red halo, and compared with the control point.