One tablet of valsartan amlodipine in the morning and one tablet of amlodipine in the evening can be used to treat high blood pressure and other conditions, but care should be taken to avoid an overdose. Amlodipine is a calcium channel blocker and can be used in the treatment of high blood pressure and other diseases. Valsartan amlodipine is a combination of valsartan and amlodipine, of which valsartan is an angiotensin inhibitor, and can be used in the treatment of high blood pressure that is not well treated with a single drug. There are no contraindications to the use of the two drugs, and the two drugs have different mechanisms but are antihypertensive drugs and can be used in combination. However, it should be noted that in general, the use of valsartan amlodipine alone does not require the addition of amlodipine if the blood pressure can be well controlled, and if it is not possible to control the blood pressure, amlodipine can be added after evaluation by a clinician. The use of valsartan amlodipine is contraindicated in cases of allergy to the components of the drug, pregnancy and lactation, hereditary angioedema, type 2 diabetes mellitus. Amlodipine is contraindicated in cases of hypersensitivity to drug components, pregnancy and lactation. Before adjusting the drug regimen, it is recommended to consult a clinician and make a decision after a comprehensive analysis, taking into account the level of blood pressure control.