Mycoplasma infections in one year old babies are usually treated for 1~2 weeks and the clinical symptoms basically improve, but according to the degree of the disease and their own physique, the treatment time varies, and the treatment time required is even longer. Mycoplasma infections can cause upper respiratory tract or lung infections, mainly fever, irritating dry cough, sore throat and other symptoms. More than a year old baby can use azithromycin and other macrolide antibiotics for treatment, according to the degree of disease and their own physical differences, the treatment time varies, the general treatment of 1 ~ 2 weeks of clinical symptoms basically improved. Mycoplasma infections can cause encephalitis, epilepsy, impaired consciousness, focal neurological symptoms, the need for intravenous application of azithromycin can cross the blood-brain barrier, the duration of the drug should be adjusted according to the child’s clinical symptoms, there is no uniform standard. It is recommended to pay more attention to drinking water during the recovery period, supplementing nutrition, disinfecting toys and maintaining air circulation. Mycoplasma infection treatment time is not a unified standard of treatment, according to the child’s body quality, immunity, nutritional status, treatment to judge, need to comply with the doctor’s prescription medication.