Antipyretic drugs are taken orally when they reach or exceed 38.5℃, because most of the accompanying symptoms of the body below this temperature are not too serious, and in most cases, the corresponding body temperature, as well as the accompanying symptoms, can be gradually relieved without medication, so oral antipyretic drugs are not particularly recommended below 38.5℃. However, if someone has a body temperature of less than 38.5°C accompanied by significant discomfort, such as particularly achy muscles throughout the body and a more intense headache, oral antipyretic medication is actually recommended. The purpose of antipyretic drugs at this time is actually not only to cool down the temperature, but also to relieve the accompanying symptoms. When the body temperature is not high and there are only obvious accompanying symptoms, they can actually be taken. So antipyretic drugs, grasping the temperature is at 38.5°C or even above, can be taken orally when it is below 38.5°C if accompanied by particularly uncomfortable symptoms.