The difference between a cold cough and a mycoplasma infected cough is that the etiology, symptoms, and treatment options are different. 1. Etiology: the pathogens that cause coughs are different. Common cold is caused by viral infection; while mycoplasma infection cough is caused by Mycoplasma pneumoniae infection. 2. Symptoms: the nature and duration of the cough are different; cold cough, accompanied by nasal symptoms, such as nasal congestion, runny nose, sneezing, etc., the symptoms will be reduced or even disappear in 1 week or so; and mycoplasma infection cough, mainly a violent dry cough, there may be a small amount of white sputum or pus sputum, etc., and the cough time will last for about 2-4 weeks. 3. Treatment plan: for cold cough, give symptomatic drugs can be; mycoplasma infection cough, give macrolides, such as azithromycin and other drugs, such as macrolides are not sensitive, can be given to quinolones such as levofloxacin. Quinolones are contraindicated in pregnant and lactating women, and in patients under 18 years of age. Cough can also be caused by other diseases, if the cough does not relieve the symptoms or accompanied by other symptoms, you should promptly go to the hospital for consultation, to identify the cause and then give targeted treatment.