Patients with symptoms of urethral pain, frequent urination, and urgency with a normal urinary routine may be due to interstitial cystitis, overactive bladder syndrome, and urethral syndrome. 1. Interstitial cystitis: Patients with interstitial cystitis often experience pain in the urethra when urinating, but normal urine routine. Patients with suspected interstitial cystitis need to undergo cystoscopy to observe whether the patient has interstitial cystitis causing painful urination. 2. Overactive bladder syndrome: patients with overactive bladder syndrome may also have urethral pain, frequent urination, urgency, while the urine routine is normal. 3. Urethral Syndrome: For older women who experience the above symptoms, estrogen deficiency may be the cause of urethral syndrome. For patients with symptoms of urethral pain, frequent urination, and urgency, and normal urinary routine, it is recommended to seek further medical examination to clarify the cause of the disease and then treatment.