Rheumatoid arthritis most often affects the joints, causing pain, joint effusion and joint deformities. Treatment is mainly with medication, exercise therapy, and surgery. There are many medications used to treat rheumatoid rheumatism: non-steroidal anti-inflammatory drugs can relieve pain and reduce inflammation. Side effects may include ringing in the ears, stomach irritation, heart disease, liver and kidney damage. Corticosteroids, such as prednisone, reduce inflammation and pain and slow joint damage. Side effects may include osteoporosis, weight gain, and diabetes. Some can slow the progression of rheumatoid arthritis and protect joints and other tissues from permanent damage. Common ones include methotrexate, leflunomide, hydroxychloroquine, and salazosulfapyridine. All of these drugs have different toxic effects and should always be used under the supervision of a doctor. Rheumatoid disease in remission requires consistent functional exercises to restore the functional impairment of the joint problems that occurred during the acute flare-up. These treatments include some physical therapies like light baking and microwaves, as well as some apparatus-assisted exercise therapies, which focus on maximizing the body’s joint function. Surgical methods are mainly for those who have more serious joint problems. Synovectomy is more commonly used. The inflamed synovial membrane is surgically removed. Synovectomy can be performed on the knees, elbows, wrists, fingers and hips to reduce the immune complex deposits that occur in rheumatoid disease and to improve joint symptoms. However, arthroplasty may be required when complete irreversible dysfunction of the joint occurs. Rheumatoid treatment is a long-term, difficult and complex process that requires effective treatment depending on the disease.