Topical glucocorticosteroid treatment of dermatological diseases was one of the major contributions to therapeutics in the last century. Since its inception, more and more corticosteroid creams have been discovered and used. This has led to the effective treatment of many skin diseases. However, at the same time, the massive and long-term topical use of hormones has also led to the occurrence of hormone-dependent dermatitis, and there is a gradual increase in the trend. So, why does long-term use lead to hormone-dependent dermatitis? This is because topical glucocorticosteroids can thin the epidermis, impair the epidermal barrier function, increase transepidermal water loss, increase the sensitivity of the skin to the outside world, and not only proliferate the sebaceous glands, but also degenerate the epithelium of the hair follicles, blocking the mouth of the follicles, resulting in acne-like lesions and capillary dilation. Diagnostic criteria: 1. Topical glucocorticoids for more than 1 month; 2. Dependence of the lesions on hormones, recurrence or exacerbation of the original disease or lesions 2-10 days after discontinuation; 3. Subjective symptoms: burning sensation, pruritus, pain, dryness, flaking, and tension; 4. Signs: microvascular dilation, erythema, flushing, edema, papules, pustules, acne, hyperpigmentation, and skin atrophy on the skin surface. The final diagnosis should be confirmed by 1 and 2 plus 3 and 4 of / or 2. Treatment: 1. Psychotherapy. 2. Alternative therapy or reduction of intensity and/or frequency of use. 3. Application of antibiotics. 4. Improvement of skin barrier function, which can be combined with medical skin care products, emolliency and moisturization. 5. Promotion of epidermal lipid barrier synthesis and formation. 6. Use of non-hormonal anti-inflammatory drugs, such as Ajinomoto, tacrolimus ointment, etc.