Which one is better, etoricoxib or diclofenac sodium, depends on the patient’s condition and individual differences, and cannot be generalized. Etoricoxib and diclofenac sodium are both non-steroidal anti-inflammatory drugs (NSAIDs), but the difference between the two is that diclofenac sodium is a non-selective cyclo-oxygenase inhibitor, while etoricoxib belongs to a selective cyclo-oxygenase inhibitor. The indications for Etoricoxib and Diclofenac sodium are also somewhat different, the indications for Etoricoxib are osteoarthritis, primary dysmenorrhea, osteoarthritis, etc., while the indications for Diclofenac sodium are inflammatory and degenerative diseases, acute attacks of gout, tenosynovitis, bursitis, etc., and the specific therapeutic drugs need to be selected according to the patient’s medical condition and individual differences and other factors. In terms of adverse drug reactions, diclofenac sodium is more irritating to the gastrointestinal tract than etoricoxib. However, Etoricoxib has a higher incidence of cardiovascular risk than diclofenac sodium. It should be noted that it should be used in small amounts for short periods of time for symptom control, and long-term use of etoricoxib and diclofenac sodium, etc. is not recommended. Drugs should be used under the guidance of a physician, and it is recommended that patients who need to take etoricoxib or diclofenac sodium go to the relevant departments of regular hospitals for consultation, and do not take the drug on their own.