Lung nodules with anterior mediastinal nodules may be caused by bacterial infections, tuberculosis, malignant tumors and other causes. Generally, medication and surgical treatment can be carried out under the guidance of a doctor. 1. Bacterial infection: Bacterial infection of the lungs generally refers to the infection caused by pathogenic bacteria, which may cause pulmonary nodules, anterior mediastinal nodules, coughing, coughing up sputum and other symptoms, can be treated with drugs such as amoxicillin and benzoxicillin under the guidance of a doctor, and nausea, vomiting, abdominal distension and other symptoms may occur after the use of the drug, and patients with a history of allergy to penicillins are prohibited from using this drug. 2. Tuberculosis: tuberculosis is often caused by Mycobacterium tuberculosis infection, often accompanied by low-grade fever, night sweats and other symptoms, the application of isoniazid, rifampicin, pyrazinamide, streptomycin and other drugs, drug nephrotoxicity, ototoxicity, neurotoxicity and so on, need to be under the guidance of a professional physician application. 2. Malignant tumors: lung nodules accompanied by anterior mediastinal nodule patients can be recommended by the doctor for pulmonary nodule resection surgery, can be removed from the naked eye can see the mass or ulcer foci, and clear lymph nodes, if necessary, postoperative application of radiotherapy, immunotherapy, targeted therapy, etc., after the operation, the patient should be regular checkups in the hospital, the diet is mainly light, prohibit spicy and stimulating food. Patients should go to the hospital, under the guidance of the doctor to actively cooperate with the treatment, the above drugs should not be taken on their own.