Acute appendicitis is the most common abdominal pain disorder. It can develop in both men and women, young and old, and pregnant women, and is especially common in young people, with an incidence rate of about 1 in 1,000. The appendix is usually located in the lower right abdomen and is a blind worm-like structure opening onto the cecum, which is called appendicitis by some because of its relationship to the cecum. Once the opening is obstructed, bacteria can cause inflammation, septicemia, necrosis and perforation, causing abdominal pain, poor appetite, lack of desire to eat, even nausea and vomiting, and in some cases, fever, bloating, lack of stool relief or diarrhea. It is common for acute appendicitis to start with pain in the upper abdomen and around the umbilicus, and after a few hours, pain in the right lower abdomen, which is then not painful in the upper abdomen and around the umbilicus. This is often referred to by doctors as metastatic right lower abdominal pain and is a characteristic manifestation of abdominal pain in acute appendicitis. There are also cases that start in the lower right abdomen, where the pain is usually not too severe, but it goes on and on without interruption. Of course, there are some patients with appendiceal ductal fecal stone obstruction who may present early with paroxysmal colic in the upper abdomen and around the umbilicus, with periods when the abdominal pain is not painful or when it is relieved. Typical appendicitis has a more constant pressure pain in the right lower abdomen, which can be felt by the patient if he or she applies finger pressure to his or her right lower abdomen. As the disease progresses, there may be rebound pain in the right lower abdomen, and the local abdominal muscles do not relax easily. Upon arrival at the hospital, a routine blood test with high white blood cells and high neutrophil ratio, an ultrasound of the appendix and a CT of the lower abdomen will clarify the diagnosis and provide a lot of reference value. The main treatment for appendicitis is to remove the diseased appendix, but conservative treatment still has its role. It is generally believed that conservative treatment can be tried in the following cases. 1. early mild appendicitis, after appropriate anti-inflammatory treatment, can be effective, the inflammation can be absorbed and subsided, the appendix can be restored to normal, and no recurrence can occur. 2. the patient’s general condition is poor or because objective conditions do not allow. 3. the onset of acute appendicitis has exceeded 48 hours, the formation of inflammatory masses, should also be used conservative treatment, to be generally 3 months before surgery The appendix should be removed, and if an abscess is formed, the abscess should be incised and drained first, and then the appendix should be removed later. 4.When the diagnosis of acute appendicitis is not clear, conservative treatment can be used while waiting for observation. 5.Conservative treatment can also be used as preoperative preparation for appendectomy. Conservative treatment includes bed rest, fasting, intravenous hydration with electrolytes and calories, along with the application of anti-inflammatory drugs, and symptomatic treatment such as sedation, anti-vomiting and analgesia. The most critical part of conservative treatment is anti-inflammatory, and the choice of anti-inflammatory drugs should depend on the specific situation. The majority of appendicitis is a mixed infection, and the combination of second- and third-generation cephalosporins with metronidazole or ornidazole is satisfactory at present. Regarding analgesia, there are still different views, and it is generally believed that appropriate analgesia can be provided after surgery has been decided. The main treatment for acute appendicitis is appendectomy, a treatment that has benefited countless people in the more than 130 years since its discovery, with 7% of people currently having had an appendectomy in their lifetime. The mortality rate of acute appendicitis was so high that even surgeons could not do anything about it, as in the case of Dr. Morton, a great surgical pioneer of the 19th century, who lost a brother and a son to acute appendicitis. Later, appendectomy was found to treat acute appendicitis, and the mortality rate was significantly reduced, and now death from acute appendicitis is very rare. Because the vast majority of patients with acute appendicitis can be treated surgically once the diagnosis is made, the diseased appendix is removed to facilitate a rapid recovery. However, the mortality rate of acute appendicitis is still high in those countries in Africa that are still very poor. The surgical options are traditional open surgery and laparoscopic surgery. Of course, the choice of surgery depends on the specific situation.