To relieve the mood irritability during menstruation, you can consider self-adjustment, appropriate confession, psychotherapy, medication and other methods, as follows: 1. Self-adjustment: During menstruation due to rapid hormonal changes and mood irritability, women can divert their attention, chat with good friends, do a proper exercise, etc., some of these methods can make their mood better. 2. Appropriate confession: You can Seek the understanding and help of friends and family members, and confide in their troubles appropriately, so that friends can help them relieve the mood problems of irritability, depression, anxiety and depression, so that they are no longer overly irritable. 3, psychotherapy: If the mood irritability is very serious during menstruation, you can consider cognitive behavioral therapy, psychoanalysis therapy or Morita therapy, etc., so that you can feel better. 4, medication: If serious mood problems occur, such as depression, anxiety, insomnia, etc. during menstruation, you can take appropriate medications for intervention, such as sertraline, lorazepam, etc., so that your mood can be quiet.