Spina bifida is a common congenital malformation. It is one of the leading causes of infant mortality and lifelong disability. So what is the pathogenesis of pediatric spina bifida? Complications of spina bifida may include bruising and edema of the lower extremities, susceptibility to trophic ulcers and even gangrene, frequent muscle contractures, sometimes hip dislocation, and horseshoe foot deformity. Spina bifida is accompanied by deformities, spina bifida may be accompanied by some other rare deformities such as: 1, fluid in the spinal cord: mostly occurs in the thoracic vertebrae, thoracolumbar or lumbosacral region, a lot of fluid accumulation in the central canal of the spinal cord, the capsule only atrophied spinal cord tissue. 2, no spinal cord: the spinal cord is not developed often accompanied by anencephaly, and death soon after birth. 3.Dermatomal cyst, lipoma or teratoma tissue: may invade the dura mater or spinal cord. The more common malformations that coexist with spina bifida are hydrocephalus, deformed foot, cranial cavity, meningeal bulge, brain bulge, cleft lip, congenital heart disease, etc.